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>   首页   >   产品   >   一抗   >   其他   >   [KO]Catalase Rabbit mAb   

[KO]Catalase Rabbit mAb

     
  • 1 - [KO]Catalase Rabbit mAb AP75198
    Western blot analysis of Catalase in HeLa(WT) and Catalase-Knockout HeLa(KO) using Catalase antibody.
  • 8 - [KO]Catalase Rabbit mAb AP75198
    Western blot analysis of Catalase in K562, rat Brain, C6, 3T3 lysates using Catalase antibody.
  • 4 - [KO]Catalase Rabbit mAb AP75198
    Immunocytochemistry analysis of Catalase (green) in Raw264.7 using Catalase antibody,and DAPI(blue)
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, FC
Primary Accession P24270
Reactivity Rat, Human, Mouse
Host Rabbit
Clonality Monoclonal Antibody
Isotype IgG
Conjugate Unconjugated
Purification Affinity Purified
Calculated MW 59795 Da
Additional Information
Gene ID 12359
Other Names Cat
Dilution WB~~1:500-1:1000
FC~~1:50-1:100
Format Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name Cat
Synonyms Cas-1, Cas1
Function Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
Cellular Location Peroxisome matrix.
Research Areas

BACKGROUND

Hydrogen peroxide is a harmful byproduct of many normal metabolic processes; to prevent damage to cells and tissues, it must be quickly converted into other, less dangerous substances. To this end, catalase is frequently used by cells to rapidly catalyze the decomposition of hydrogen peroxide into less-reactive gaseous oxygen and water molecules. Catalase is usually located in a cellular, bipolar environment organelle called the peroxisome. All known animals use catalase in every organ, with particularly high concentrations occurring in the liver. Catalase promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.

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